Issacs was influential to many Reggae artists from the 1970′s to present day. Although in the 70′s and 80′s his popularity rivaled those of Dennis Brown and Bob Marley, it wasn’t until 1992 that he had his biggest hit called ”Night Nurse”. The guy had a string of hits prior to that outside the US, but this was the one hit that gave him the most noteriety. Issac’s performed and released albums up until 2008. Issacs had released over 500 albums (both studio and compilations) over his career.
Issacs struggled with drugs for years and ultimately succumbed after a long battle with lung cancer; he died in his home in South London.
Appearently the band Phish covered “Night Nurse” at a concert in Manchester NH the night after he died ; a fitting tribute for sure.